References

  1. Ling Wang, Jinhua Tang, Lei Wang, Feng Tan, Huibin Song et al. Oxidative stress in oocyte aging and female reproduction. J Cell Physiol. 2021;1–18 Hiroshi Tamura, Mai Jozaki, et al. Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging. Int. J. Mol. Sci. 2020, 21, 1135. Liuqing Yang,Yun Chen et al. The Role of Oxidative Stress and Natural Antioxidants in Ovarian Aging. Front. Pharmacol., 14 January 2021 | https://doi.org/10.3389/fphar.2020.617843.
  2. EU Register on Nutrition and Health Claims. Zinc (Art.13(1), 2009;7(9):1229), Selenium (Art.13(1), 2009;7(9):1220), Vitamin C (Art.13(1), 2009;7(9):1226), Vitamin E (Art.13(1), 2010;8(10):1816). https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/?event=register.home
  3. EU Register on Nutrition and Health Claims. Zinc (Art.13(1), 2009;7(9):1229). https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/?event=register.home
  4. EU Register on Nutrition and Health Claims. Folic Acid (Art.14(1)(a), Q-2013-00265). https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/?event=register.home Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus. The beneficial effect for women of child-bearing age is obtained with a supplemental folic acid daily intake of 400 μg for at least one month before and up to three months after conception. The disease to which the claim is referring has multiple risk factors and that altering one of these risk factors may or may not have a beneficial effect.
  5. EU Register on Nutrition and Health Claims. Vitamin B16 (Art.13(1), 2009;7(9):1225). https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/?event=register.home
  6. Ruder, E. H., Hartman, T. J., Reindollar, R. H., & Goldman, M. B. (2014). Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertility and Sterility, 101(3), 759–766. doi:10.1016/j.fertnstert.2013.11
  7. Agarwal, A., Aponte-Mellado, A., Premkumar, B. J., Shaman, A., & Gupta, S. (2012). The effects of oxidative stress on female reproduction: a review. Reproductive biology and endocrinology : RB&E, 10, 49. https://doi.org/10.1186/1477-7827-10-49
  8. Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategies. Reprod Med Biol (2015) 14:159–169
  9. May-Panloup P, Boucret L, Chao de la Barca JM, et al. Ovarian ageing: the role of mitochondria in oocytes and follicles. Hum Reprod Update 2016; 22(06):725–743
  10. Tilly JL, Sinclair DA. Germline energetics, aging,and female infertility. Cell Metab 2013;17(06):838–850
  11. Kasapoğlu I, Seli E. Mitochondrial dysfunction and ovarian aging. Endocrinology 2020;161(02):bqaa001
  12. Homer, H. A. (2020). The Role of Oocyte Quality in Explaining “Unexplained” Infertility. Seminars in Reproductive Medicine.